Best Online
GLP-1 & Weight-Loss Programs

Best for: Cash-pay buyers who want one flat monthly figure covering medication, clinician review, delivery and check-ins, with no separate pharmacy bill to reconcile. It also suits people whose dose is likely to rise, because TrimRx states the monthly cost does not move when the dose does. It is a weaker fit if you want a named compounding pharmacy, published refund terms, or structured coaching before you commit.

Pricing: Two published plans: GLP-1 from $179 per month and GLP-1 + GIP from $259 per month (TrimRx plan cards, checked 16 September 2026). TrimRx states the price covers the consultation, the medication, custom dosing, delivery and unlimited check-ins, with no insurance required, and that "your treatment cost remains steady, even as your dose changes". A provider may instead write a prescription for an FDA-approved branded medication, which TrimRx does not sell, dispense or ship — that route is filled at a pharmacy of your choosing and paid for separately.

Best for: People who want a familiar, well-known digital-health brand with insurance-aware GLP-1 pathways and the option to pursue coverage rather than pay full cash price.

Pricing: Ro Body membership is $39 for the first month, then $74–149/month depending on the plan you choose — the $74/month rate applies only to the 12-month plan, prepaid annually. Ro states the $39 is refunded if you are not eligible for GLP-1s. GLP-1 medication is a second, separate charge on top of membership: oral Wegovy (semaglutide) from around $149/month and Zepbound (tirzepatide) from around $299/month cash-pay. An insurance concierge pursues coverage, so eligible patients may pay closer to a copay.

Best for: Buyers who want one provider for both a GLP-1 and the longevity side, such as sermorelin, NAD+, glutathione and MIC+B12, rather than a second subscription elsewhere, and who are willing to commit for twelve months to get the lowest rate. It is a poor fit for anyone who might stop early: once a prescription reaches the pharmacy bmiMD's policy is that all sales are final.

Pricing: Priced per treatment, each shown as a list price against a discounted subscription rate (checked 23 September 2026). Compounded GLP-1 (semaglutide) from $119/month on a 12-month plan, rising to $129 at 6 months, $149 at 3 and $159 monthly, against a $228.60 list. Compounded GLP-1/GIP (tirzepatide) from $179/month at 12 months, $189 at 6, $229 at 3 and $249 monthly, against a $349.20 list. Microdose options from $119 (semaglutide) and $179 (tirzepatide). Metformin ER from $37, MIC+B12 from $69, sermorelin tablets from $79, sermorelin injection from $99, sermorelin nasal spray from $109 (the sermorelin tablet and nasal spray re-read 26 September 2026), NAD+ injection, NAD+ nasal spray and glutathione from $119, naltrexone/bupropion/B6 from $166.33. bmiMD states the price is the same at every dose, that shipping is free, and that there are no hidden fees.

Best for: Users who want a broader telehealth provider that covers GLP-1 plus general wellness, rather than a single-focus weight-loss clinic.

Pricing: Pricing varies by treatment path; confirm before starting intake

Best for: Users weighing GLP-1 alongside non-GLP-1 weight-loss options or NAD+ support in the same program.

Pricing: Pricing varies by program path; check state availability before signing up

Best for: Buyers who want one provider for weight management, longevity, hair and sexual health, and who will read the commitment length before reading the price. Shed publishes a wider menu than most, with six longevity treatments, seven hair products and five for sexual health, and prices nearly all of them. It suits nobody who takes the advertised “from $159/mo” at face value: that is the twelve-month rate, month-to-month is $199, and subscriptions cannot be cancelled for the first two months.

Pricing: Compounded semaglutide is $199 a month on a one-month plan, $179 on six months and $159 on twelve; compounded tirzepatide is $299, $269 and $239 on the same three. Microdose compounded semaglutide is $149 a month and microdose tirzepatide $199. Foundayo (the oral GLP-1), Wegovy and Zepbound are each $149 a month plus a separate $125 a month Shed Membership. Checked 20 September 2026.

Best for: Users who want a lower-commitment online GLP-1 start with ongoing telehealth messaging.

Pricing: Compounded GLP-1 injections from $79 per month and compounded GLP-1/GIP injections from $129 per month. Sermorelin, NAD+ and glutathione are each a flat $99 per month under a limited sale Embody describes as $100 off. The price is fixed for a given medication regardless of dose and changes only if you switch medication or plan length; plans run 4, 12, 24 or 52 weeks. No membership fee, and shipping is free and expedited. Checked 12 September 2026.

Best for: Users comparing newer online weight-loss programs alongside the best-known brands.

Pricing: Pricing varies; verify the full plan cost directly with Gala

Best for: Buyers researching peptides for longevity, recovery and healthy ageing rather than weight management alone. System Labs publishes a per-treatment price for every item on its menu, names the compounding pharmacy it partners with, and states that it operates in all 50 states — three things much of this segment leaves unsaid. It also suits people who want both an injectable and a non-injectable route for the same compound, since sermorelin, NAD+, glutathione and GHK-Cu are each offered in more than one form.

Pricing: Published per-treatment prices, read from System Labs' own catalogue on 18 September 2026: NAD+ injection $149/month ($89 first month); NAD+ nasal spray $119/month ($69); glutathione injection $149/month ($79); glutathione nasal spray $169/month ($79); sermorelin injection either $219/month ($109) or $175/month ($89); oral compounded sermorelin either $159/month ($79) or $140/month ($70); GHK-Cu $109/month and MIC+B12 $89/month, neither of which carries an introductory rate. Every introductory rate is first-month only and reverts to the ongoing price afterwards, each treatment is billed separately with no bundle, and System Labs states that refills are automatic. System Labs is cash-pay only and states that no insurance is accepted.

Best for: Users who want an online GLP-1 weight-loss pathway connected to a familiar fitness, nutrition, and training brand.

Pricing: Pricing varies by medication path; confirm the full monthly cost before signing up

Best for: Buyers who want the supply chain written down before they pay. MEDVi is one of the few programmes at this price point that names its partner pharmacies, names the prescriber network, and publishes a full cancellation and refund policy. It also suits people weighing a compounded plan against a branded one on the same platform, since it prices both.

Pricing: Compounded GLP-1 injections from $179 per month and compounded GLP-1 tablets from $249 per month. Branded routes are sold differently, as a $99 membership plus the cost of the medication itself. MEDVi states there is no membership fee or hidden fee on the compounded plans, that no insurance is required, that shipping is free, and that the plans are HSA/FSA approved. Checked 16 September 2026.

Best for: Buyers who are confident they will stay on treatment for a year and can pay for it upfront. That is the only way Trimi's headline monthly figures are available. It also suits people who want the supply chain named: Trimi publishes its prescriber group, its two compounding pharmacies and two named physicians, and backs the plan with a six-month money-back promise.

Pricing: Compounded semaglutide at a $99 monthly equivalent, billed as $1,188 upfront on a 12-month commitment, or $175 per month with no commitment. Compounded tirzepatide at a $125 monthly equivalent, billed as $1,500 upfront on a 12-month commitment, or $235 per month with no commitment. Trimi states the plans include the medication if prescribed, supplies, licensed provider care and ongoing support, and free overnight shipping once compounded. Checked 16 September 2026.

Best for: Buyers who want a choice of route rather than the cheapest entry price. Willow is the only programme on this list publishing four distinct GLP-1 formats, injection or daily tablet, single-agonist or dual-action, plus NAD+, all under one flat monthly price with unlimited doctor access included.

Pricing: Per-treatment pricing, checked 16 September 2026: semaglutide injection $299/month, semaglutide tablets $299/month, tirzepatide injection $399/month, tirzepatide tablets $399/month and NAD+ $199/month. Willow states the price includes the personalised GLP-1 medication, the medical evaluation and treatment plan, unlimited access to your Willow doctor, 24/7 online support from the care team, and free discreet shipping, with no hidden fees and no insurance required. Plans are FSA and HSA eligible. Checked 16 September 2026.

Best for: Adults in the six provinces Felix serves who want a prescription assessed without booking an appointment, and who are comfortable being assessed in writing rather than by video. It suits people without a family doctor, and stable treatment that needs renewing rather than re-diagnosing. If you live in Quebec, New Brunswick, Nova Scotia, Newfoundland and Labrador or the territories, or need the consultation covered by a provincial plan, Felix is not set up for that. If you want a particular clinician, Felix says it can honour that on request.

Pricing: The consultation and the medication are billed separately. Initial visit fees are set by category: $40 for most, $99 for menopause and mental health, and $150 for diabetes and metabolic care. The initial weight-management visit fee is currently waived. Erectile dysfunction and HIV prevention were $0 when checked. Birth control is $40 and STI testing is $55. Follow-ups are $0 to $40 depending on the category. Medication is charged on top, plus a $12.00 fill fee per drug on every refill. Shipping is free.

Best for: Buyers who want a flat monthly price that does not climb as the dose climbs, and who are willing to accept a consultation fee of $50 to $100 that is charged before a clinician looks at their case and is not refunded if they turn out to be ineligible.

Pricing: Checked 23 September 2026 on CoreAge's own public pages. Semaglutide $99 a month and tirzepatide $149. Semaglutide microdosing $149 and tirzepatide microdosing $199. NAD+ as an injection or a nasal spray, both $93. Sermorelin $99. A separate partner landing page sells two cheaper plans that are capped by dose: semaglutide at $79 a month capped at 1 mg, and tirzepatide at $129 capped at 7.5 mg. Those are different products from the $99 and $149 plans rather than a discount on them, which is the single most confusing thing about CoreAge's pricing. Shipping is free.

Best for: People in the US who want an online assessment reviewed by a licensed clinician, with any prescribed treatment shipped from a pharmacy, and who want the dispensing pharmacies named before they start. Anyone weighing it should read REBL's own disclaimer first: compounded medications are "not reviewed by the FDA for safety or effectiveness".

Pricing: REBL publishes a starting monthly price for five treatments, each worded "Treatments from". For weight management, Compounded Semaglutide is from $55/mo and Compounded Tirzepatide is from $199/mo. Glow Blend (Hair, Skin & Nails) is from $215/mo. Dihexa is from $229/mo and Semax + Selank is from $269/mo; those two are covered in a section of their own below.

Best for: Men in the US who want one monthly membership covering testosterone replacement therapy, thyroid medication, erectile dysfunction treatment, GLP-1 therapy and supplements, and who accept that medication is billed on top at a price Male Excel does not publish.

Pricing: Membership $99 per month. Medications billed separately at member pricing, not published. No insurance accepted. Checked 2 October 2026.

Best for: Buyers who want a wide menu from one provider. Eden sells compounded and branded GLP-1 side by side, plus NAD+ in three forms, sermorelin, MIC+B12 and a hair kit, all under one clinician relationship. It suits someone comparing a compounded route against a branded one on the same platform.

Pricing: Checked 28 September 2026 on Eden's own pages: compounded semaglutide $99/month and compounded tirzepatide $129/month, and Eden states "No membership fees" and "There is no separate membership fee". Eden says the monthly price includes provider review, clinical support, messaging, dose guidance and delivery. Checked 19 September 2026: a Custom Weight Loss Kit from $34 for the first month; branded Ozempic, Zepbound and Mounjaro at $1,399/month and Wegovy at $1,695/month; sermorelin injections from $126 for the first month; NAD+ nasal spray from $112 and NAD+ face cream from $84; a Custom Hair Growth Kit from $83; and MIC+B12 from $73 for the first month. Eden quotes NAD+ injections two ways — from $91 on its weight-loss and reviews pages and from $119 on its homepage — and this page reports both. Eden states shipping is free on all orders and that HSA and FSA are accepted for most visits and prescriptions.