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A US telehealth platform selling compounded semaglutide and tirzepatide on annual plans billed upfront, at the lowest monthly equivalents on this list, with month-to-month rates roughly 75% higher. Prescribing runs through Arora Health; compounding is by two named 503A pharmacies.
Quick verdict
Trimi is the cheapest twelve-month option here and the most explicit about what it will refund and when, but the headline price is an annual prepayment rather than a monthly rate, and the point of no return arrives earlier than on any other programme on this list — at prescription, not at shipping.
Buyers who are confident they will stay on treatment for a year and can pay for it upfront — that is the only way Trimi's headline monthly figures are available. It also suits people who want the supply chain named: Trimi publishes its prescriber group, its two compounding pharmacies and two named physicians, and backs the plan with a six-month money-back promise.
This profile is designed to help users compare the program before beginning intake. It is not a recommendation that any treatment is appropriate.
Compounded semaglutide at a $99 monthly equivalent, billed as $1,188 upfront on a 12-month commitment, or $175 per month with no commitment. Compounded tirzepatide at a $125 monthly equivalent, billed as $1,500 upfront on a 12-month commitment, or $235 per month with no commitment. Trimi states the plans include the medication if prescribed, supplies, licensed provider care and ongoing support, and free overnight shipping once compounded. Checked 16 September 2026.
The $99 and $125 figures are monthly equivalents of annual billing, not monthly prices — the cash outlay on day one is $1,188 or $1,500. Compare the no-commitment rates against other providers before treating Trimi as the cheapest option.
Availability varies by state and clinical eligibility.
Compounded semaglutide (GLP-1) and compounded tirzepatide (GLP-1/GIP), prescribed only after evaluation by a licensed provider. Trimi states that compounded medications are not FDA-approved and that the FDA does not review them for safety, effectiveness or quality.
Online visit and health history reviewed by a licensed provider through Arora Health, who determines whether a prescription is appropriate. Trimi states that choosing a plan does not mean you are eligible or approved.
Free overnight shipping once the medication has been compounded.
Trimi publishes two medications at two commitment levels. Compounded semaglutide is shown at $99 a month and compounded tirzepatide at $125 a month — but Trimi states plainly that "prices shown are monthly equivalents of annual billing", and the annual figures are $1,188 and $1,500, billed upfront. Without the twelve-month commitment the same treatments are $175 and $235 a month. That is a 77% and 88% difference between the advertised figure and the month-to-month one, which makes the headline the least useful number on the page.
What the plans include is consistent across both: the medication if prescribed, supplies, licensed provider care and ongoing support, and free overnight shipping once the medication has been compounded. There is no separate membership fee. The care team is stated to be available 24/7 with a one-hour response target, which is the most specific support commitment among the programmes on this list.
The honest way to read Trimi's pricing is as an annual product. If you complete twelve months it is the cheapest option here by a clear margin — $1,188 against roughly $2,148 for a year at TrimRx's $179, or $2,148 at MEDVi's. If you stop at month three, you have paid a year in advance for a plan whose refund rules, set out below, are strict.
Trimi's refund policy, last updated 11 September 2026, turns on a single moment: whether a clinician has issued your prescription. Before that, you can cancel at any time for a full refund with, in its words, "no questions, no fees". After it, the order is final — not when the medication ships, but when the prescription is signed. Trimi explains why: a compounded preparation is made for one named patient, and under USP <795> and <797> and state pharmacy rules it cannot be re-dispensed to anyone else even if it never left the pharmacy.
That is a genuine legal constraint rather than a commercial choice, and every provider in this segment faces it. What differs is where each draws the line. MEDVi's cooling-off window runs 72 hours from the start of the subscription term; Trimi's runs until the prescription is written, which may be sooner or later depending on how fast the clinician review moves. If a clinician decides treatment is not appropriate for you, Trimi refunds everything including the consultation fee.
On top of that sits the six-month money-back promise, which no other provider on this list matches. Complete six continuous months on the prescribed plan and if you are still not satisfied, or have not lost weight, Trimi refunds the plan fees. The conditions are published and they are strict: an active paid plan, medication taken on schedule at the prescribed dose, provider check-ins completed, and both a starting weight and a six-month weight logged in the patient portal. A pause, an early stop or skipped doses void it, and without both logged weigh-ins a no-results claim cannot be verified and will not be approved. It is a real promise with real conditions, and the conditions are the part to read.
Trimi states that its compounded prescriptions are prepared by BelieveRx and GreenwichRx, both described as state-licensed 503A pharmacies. A 503A pharmacy compounds for an identified individual patient against a prescription, which is the category these GLP-1 programmes operate in; it is a different regulatory footing from a 503B outsourcing facility, which makes larger batches and registers with the FDA. Neither is an FDA review of the finished medicine.
Prescribing runs through Arora Health, and Trimi names two physicians — Dr. Sean Arora, MD and Dr. Shannon Arora, MD — with individual profile pages. Naming the prescribing clinicians is rare in this segment, and it makes the licence verifiable through a state medical board in a way that "a network of licensed providers" does not.
Trimi's regulatory wording is short and unambiguous: "Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness, or quality. Treatment requires an individual evaluation and a prescription." It repeats the point next to each plan card rather than burying it in a footer.
Trimi and MEDVi are the two programmes on this list that name their pharmacies, which makes them the natural pair to compare. On twelve-month cost Trimi wins clearly: $1,188 for semaglutide against MEDVi's $179 a month. On flexibility MEDVi wins: it asks for nothing upfront and allows cancellation at any time with 72 hours' notice, where Trimi's cheapest rate requires a full year's prepayment and becomes non-refundable at prescription.
Against TrimRx, Trimi is cheaper over a year but requires the year; TrimRx's $179 and $259 sit above Trimi's annual equivalents and below its month-to-month rates. TrimRx also states its price does not move as the dose changes, a commitment Trimi does not make either way. Against Willow at $299 a month, Trimi is cheaper on both its plan types.
One thing on Trimi's site should be set aside when judging it. It carries an "in the news" strip linking to ConsumerAffairs, Men's Journal, Vice and a sponsored WebMD placement, and it publishes blog posts ranking rival providers. Those are advertising and commercial content, not independent assessment, and they are not sources for anything on this page — the facts above come only from Trimi's own product and policy pages.
Trimi is an identifiable, operating US telehealth service that publishes more about its supply chain than most of its competitors: two named 503A compounding pharmacies, a named prescriber group, two named prescribing physicians with profile pages, and a dated refund policy. We found no LegitScript seal or other certification marker on its site, which several competitors do display. As always, none of this speaks to whether treatment is appropriate for you.
No. Trimi's own wording, repeated beside each plan, is that "compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness, or quality. Treatment requires an individual evaluation and a prescription." Its pharmacies are described as state-licensed 503A pharmacies, which compound against an individual prescription and are regulated by state boards rather than reviewed as finished products by the FDA.
Checked 16 September 2026. Compounded semaglutide: $99 a month as a monthly equivalent of $1,188 billed upfront on a twelve-month commitment, or $175 a month with no commitment. Compounded tirzepatide: $125 a month as a monthly equivalent of $1,500 billed upfront on a twelve-month commitment, or $235 a month with no commitment. The plans include medication if prescribed, supplies, provider care and free overnight shipping.
Only as an annual equivalent. Trimi states that "prices shown are monthly equivalents of annual billing" — the $99 figure means $1,188 charged upfront for twelve months. If you want to pay monthly, semaglutide is $175 and tirzepatide $235. Both figures are published on Trimi's own plan cards; the distinction is worth making because the two numbers differ by roughly three-quarters.
Before a clinician issues your prescription, yes — Trimi states you can cancel any time for a full refund with no fees. After the prescription is issued the order is final and cannot be cancelled, even if the medication has not shipped, because a compounded preparation is made for one named patient and cannot legally be re-dispensed. If a clinician decides treatment is not appropriate for you, Trimi refunds everything including the consultation fee. Damaged or missing packages must be reported within 24 hours.
Trimi states that if you stay on your plan through the first six months and follow your provider's guidance, and you are still not satisfied or have not lost weight, it will refund the plan fees you paid. The published conditions are strict: an active paid plan, medication taken on schedule at the prescribed dose, provider check-ins completed, and both a starting weight and a six-month weight logged in your patient portal. Pausing, stopping early or skipping doses voids it, and a no-results claim cannot be approved without both logged weigh-ins.
Trimi states that its compounded prescriptions are prepared by BelieveRx and GreenwichRx, both state-licensed 503A pharmacies. It does not say which of the two fills a given order. Prescribing is through Arora Health, and Trimi names Dr. Sean Arora, MD and Dr. Shannon Arora, MD as prescribing physicians.
In our evaluation: the advertised price is an annual prepayment rather than a monthly rate, and the month-to-month alternative is roughly 75% higher; the point of no return arrives at prescription rather than at shipping, which is earlier than competitors; and the six-month promise, while real, requires unbroken adherence and logged weights that many people will not maintain. It also publishes no list of states served and no certification seal.
Finished the review? Check current availability and pricing for Trimi directly.
Trimi is the cheapest twelve-month option here and the most explicit about what it will refund and when, but the headline price is an annual prepayment rather than a monthly rate, and the point of no return arrives earlier than on any other programme on this list — at prescription, not at shipping.
PCF reviews online programs for comparison purposes only. Provider details, pricing, availability, and medication paths can change. Confirm current terms directly and consult a licensed clinician before making medical decisions.