Sermorelin: what it is, what it costs per month and where to buy it online in the US

What sermorelin is

Sermorelin is a synthetic peptide made of the first 29 amino acids of growth hormone-releasing hormone, the hormone that signals the pituitary gland to release growth hormone; trials often name it by that structure, GHRH(1-29). It is not growth hormone itself and acts one step earlier in the same pathway. It is usually supplied as sermorelin acetate, the salt form, which is why “sermorelin acetate price” and “sermorelin price” are the same question.

Sermorelin was an FDA-approved medicine under the brand name Geref, first in 1990 as a diagnostic test of the pituitary and in 1997 as a treatment for children with growth hormone deficiency. Its manufacturer stopped selling it in 2008, and FDA withdrew both approvals in 2009. Everything sold under the name today in the US is compounded: prepared by a pharmacy against an individual prescription. What has and has not been studied is set out in the evidence section below, with each source linked.

How sermorelin is prescribed online

Every provider on this page follows the same shape. You complete an online medical intake, a licensed clinician reviews it and decides whether to prescribe, and if they do, a compounding pharmacy prepares the sermorelin and ships it to you. The price you pay is a subscription that covers the medication and, at most providers, the review; a prescription is never guaranteed, and a provider that charges before the review should say what happens to that payment if you are found ineligible.

Sermorelin is not sold over the counter and is not an FDA-approved product, so it is not a thing you can buy without that review. Sermorelin sold on the open web as a “research” product is a different market: it is not dispensed on prescription, and this page does not cover it or its prices.

Injection or tablet: what the choice changes

The injection is given subcutaneously, by you, on the schedule your prescriber sets. The tablets dissolve under the tongue or in the mouth and involve no needle. Two of the six providers here sell a tablet. At bmiMD it costs less than the injection; at System Labs it costs less than the injection.

bmiMD also sells a nasal spray, a third route and the only one on this page. On its lowest plan length it costs $129 a month, against $89 injected and $69 as a tablet. bmiMD publishes no dose for it.

No provider publishes a comparison of how much sermorelin each route delivers, and none of the sources in the evidence section below compares them either. This page therefore does not say one route works better than another. If the needle is the deciding factor, the tablet and the nasal spray exist; that is what the published information supports.

If the tablet is what you want to look at, these links go to each seller's sermorelin page, the tablet page where one exists, in the table's order: bmiMD and System Labs. We earn a commission on these links, as on the partner links further down.

Sermorelin cost per month in the US right now: the price table

Every figure below was read from the provider's own live page on the date shown, and the page it came from is linked. Nothing here is estimated, interpolated between plan lengths, or taken from a third-party round-up. Where a provider publishes no dose or supply, the column says so rather than being filled in. Rows are ordered by route and then alphabetically, never by price. Wellorithm also sells sermorelin online, but it publishes a starting price rather than a supply or dose breakdown, so it is not in the table; our Wellorithm review covers what it does publish.

• bmiMD, injection: Read from the Sermorelin Injections card on bmiMD's homepage, a "Starting as low as" figure. It is the lowest of bmiMD's plan lengths, its 6-month plan (bmiMD offers no 12-month sermorelin plan), so a reader who signs up month to month pays more. The card strikes through a higher figure beside it; bmiMD does not call that a standard price. The product page says there are no hidden membership fees and that consultations are at no cost. bmiMD serves automated requests a browser check.
• CoreAge Rx, injection: Published as a "Starting at" price per month, so the price can rise with the dose or plan. The page states no membership fees, no long-term contracts and fast, free delivery, and that the product is compounded in the USA. It publishes no dose.
• Embody, injection: Shown under a "LIMITED PRE-BLACK FRIDAY SALE" banner worded as money off the first month and every month after. Embody states no standard price and gives no end date for the sale, so the figure cannot be read as a standing price. A free online medical evaluation and the prescription and telemed visits are stated as included, and the page says no insurance or bloodwork is required. Embody's own page says sermorelin "is not intended for anti-aging, bodybuilding, or athletic performance purposes".
• Hone Health, injection: Hone charges it on top of a monthly membership (Basic or Premium), so the monthly total is higher than the treatment price. The page says it is a compounded product that has not been approved by the FDA.
• Luvo Health, injection: Luvo bills every 4 weeks (28 days) rather than monthly, which is 13 billing cycles a year rather than 12. Its product page has shown a discounted first 4 weeks. The page states there are no membership fees, and that compounded medications are not FDA-approved.
• Shed, injection: Shed's sermorelin page shows one plan, a 1-month supply stated as "Taken 5 times weekly", and its longevity page lists the same treatment. It publishes no dose.
• System Labs, injection: Read from System Labs' own pages, and read again every day from its treatments page. On October 18, 2026 the same page's billing FAQ still quoted a different, higher first-month and monthly price, and on September 29, 2026 we documented a live price test showing each new visitor one of two sets of prices. Confirm the ongoing price in writing before you pay.
• bmiMD, sublingual tablet: Read from the Sermorelin Tablets card on bmiMD's homepage, a "Starting as low as" figure on its lowest plan length. The product page states the tablets are "Available in 49 States", against "All 50 States" for the injection, and publishes no dose.
• System Labs, oral dissolving tablet: Read from System Labs' own pages, and read again every day from its treatments page. The $79 rate is first month only. On September 29, 2026 we documented the same live price test on this page as on the injection page.
• bmiMD, nasal spray: Read by hand from bmiMD's sermorelin nasal spray page: the lowest of its plan lengths, with a higher monthly figure struck through beside it. The page publishes no dose and no supply quantity, and states no separate consultation fee and no membership fee.

Where to buy sermorelin online: the providers we work with

Six providers we work with that sell sermorelin are listed below in the same order as the table: alphabetically. That order is not a ranking. We earn a commission if you buy through these links, and the commission differs between providers; that changes nothing about the order, the prices above or what we publish about any of them.

PlexusDx also prescribes sermorelin, alongside NAD+, glutathione and its GLP-1 plans, after an online visit. We have not recorded its sermorelin price, so it is not listed above; our review of PlexusDx's sermorelin and other peptides covers how it prescribes them. Compounded medicines are not FDA approved.

Is sermorelin FDA approved? Compounded medicines, and what that word means here

Every sermorelin product on this page is compounded. That means it is prepared against an individual prescription by a compounding pharmacy rather than manufactured as a finished product and reviewed by the FDA. It is a distinct regulatory category: not approved, and not unlawful either.

Sermorelin is unusual in having once been an approved medicine. It was sold as Geref until its manufacturer discontinued it in 2008, and FDA later determined that the withdrawal was not for reasons of safety or effectiveness. No approved sermorelin is sold in the US today, so every option here is a compounded one, and the pharmacy that prepares it carries more of the responsibility than it would for a branded medicine. Embody's sermorelin page names its partner pharmacies. For any provider, it is worth asking which pharmacy prepares your prescription before you pay.

What the evidence shows, and what it does not

The short answer is that sermorelin was studied mainly as a treatment and a diagnostic test for children with growth hormone deficiency, and that the evidence for the adult uses it is marketed for today is thin. That is a statement about what has been studied, not a finding that sermorelin does or does not work, and each point below is taken from a source listed at the end of this section.

Regulatory history. Sermorelin acetate was approved by the FDA as Geref twice: in 1990 as a test of the pituitary gland's ability to release growth hormone, and in 1997 to treat idiopathic growth hormone deficiency in children with growth failure. The manufacturer, EMD Serono, told the FDA in 2008 that it was discontinuing both products, and the FDA withdrew both approvals effective June 18, 2009. In 2013 the FDA determined that neither product was withdrawn from sale for reasons of safety or effectiveness. FDA's drug approvals data lists no other sermorelin product, and both Geref entries are marked discontinued.

What has been studied in people. Sermorelin is the first 29 amino acids of the hormone that signals the pituitary to release growth hormone, and trials often name it by that structure, GHRH(1-29). In a 1993 randomized trial, 60 children with growth hormone deficiency received sermorelin at one of two doses, or growth hormone, for 6 months. Growth was significantly greater on growth hormone: 14.6 cm a year, against 9.2 and 9.3 cm on the two sermorelin doses. Almost every child on sermorelin, 39 of 40, developed antibodies to it, which had almost disappeared 9 months after stopping, and the authors concluded that it was unlikely to be as effective as growth hormone for promoting growth.

What has not been established. A PubMed search on September 25, 2026 found no systematic review or meta-analysis of sermorelin. A 2026 review of peptides that act on the growth hormone axis states that clinically meaningful benefits in healthy individuals remain uncertain, because the human evidence base is limited and largely indirect. It records that sermorelin has no current regulatory approval for performance or body-composition uses, and that no long-term safety data are available. A second 2026 review, covering unapproved peptides sold direct to patients as a group, describes rigorous human safety data as scarce. None of the sources here reports an effect on appearance, aging or lifespan in adults.

Sermorelin side effects: what the sources list

The 2026 review in the sources above lists injection-site pain, short-term flushing, nausea, dizziness and headache, rare allergic reaction, and a small, transient rise in the hormone prolactin. In the 1993 trial, three children reported mild irritation at the injection site and no serious side effects were seen. None of this was measured for the compounded products sold on this page, so their side effect profile is not established in either direction, and no long-term safety data are available.

This is a summary of what has been published, not an assessment of what sermorelin would do for you. Talk to a clinician about your own history and medications before you start, and about anything you notice after you do; every provider on this page includes a clinician review, and that is the place for those questions.

Questions to ask before you pay

• Is the advertised price the ongoing one, or a first month, a first 4 weeks or a long commitment? Every provider here quotes one of those.
• Is the plan billed monthly, every 4 weeks or quarterly, and what is the price if you stop early?
• Which compounding pharmacy prepares it, and will they name it before you order?
• What supply does the price cover, and does it change if your prescriber changes the dose?
• Is the product available in your state, and is that confirmed before payment or after?

Frequently asked questions