Tools

BPC-157 + TB-500 blend calculator

A blended vial holds two peptides in one solution, so one volume drawn delivers both — and the arithmetic has to be run twice, once per component. Enter the component you want to be exact about; the volume that satisfies it fixes the other.

Calculator

Enter your own vial strength, water volume and dose.

Draw to

15units

on a U-100 insulin syringe (0.15 ml)

025507510015u
Concentration
3.33 mg/ml
3333.33 mcg/ml
Volume to draw
0.15 ml
Doses per vial
20
Syringe capacity
100 units

How this is calculated

concentration (mg/ml)  = vial mg / water ml            = 10 / 3 = 3.33
concentration (mcg/ml) = concentration mg/ml x 1000    = 3333.33
volume to draw (ml)    = dose mcg / concentration mcg  = 500 / 3333.33 = 0.15
insulin units          = volume ml x 100               = 0.15 x 100 = 15
doses per vial         = floor(water ml / volume ml)   = floor(3 / 0.15) = 20

100 units = 1 ml on every U-100 insulin syringe. Barrel size changes how much it holds,
never what a unit means.

What a blended vial actually contains

Blends are sold with a combined figure on the label — a "10mg blend" — and that figure is the total mass of both peptides, not the mass of either. A 5mg/5mg blend and a 7mg/3mg blend can both be labelled 10mg while behaving completely differently at the syringe. Before any calculation is meaningful, you need the split, and it comes from the supplier's own documentation rather than from the total.

Once you have it, a blend is two ordinary reconstitution problems that happen to share a volume of water. If 3ml goes into a 5mg/5mg vial, the solution is 1667 mcg/ml of each component. If it goes into a 7mg/3mg vial, it is 2333 mcg/ml of one and 1000 mcg/ml of the other, in the same millilitre.

Why one volume cannot be exact for both

This is the part a single-compound calculator cannot express. You draw one volume, and that volume delivers a fixed ratio of the two components — the ratio the vial was blended at. You can be exact about one of them; the other follows. From a 7mg/3mg blend in 3ml, a volume carrying 500mcg of the first component carries about 214mcg of the second, and no choice of water volume changes that ratio. Water changes both concentrations together.

So the practical method is to decide which component you want to control, run the arithmetic for that one, and read what the same volume gives of the other. Run the calculator above twice — once with each component's mass as the vial figure — and compare. If the second figure is not acceptable, the blend ratio is wrong for the purpose, and no reconstitution volume will fix it.

Storage, and one extra caution for blends

Storage is as for either peptide alone: sealed powder keeps well cool, dry and dark; reconstituted solution needs refrigeration and has a life measured in weeks, shortened by heat, light and agitation. Bacteriostatic water permits repeated entry, plain sterile water does not.

The extra caution is that a blend cannot be separated once mixed. With two single vials you can adjust each independently; with a blend you have committed to the ratio in the vial, and the only variable left is how much you draw. That is worth knowing before the water goes in rather than afterwards.

Frequently asked questions

How do I calculate a blend if the label only gives a total?

You cannot, and the total is not enough. A 10mg blend might be 5mg/5mg or 7mg/3mg, and those give different concentrations for each component in the same volume. Get the split from the supplier's documentation first, then run the arithmetic once per component.

Can I make both components come out exact?

No. One volume delivers the ratio the vial was blended at. You can be exact about one component; the other is whatever that same volume carries. Changing the water volume changes both concentrations together and leaves the ratio untouched.

How do I use this calculator for a blend?

Run it twice. Enter the mass of the first component as the vial figure with your water volume, and note the units for the amount you want. Then enter the mass of the second component with the same water volume, and read what that same volume delivers of it.

Does a blend need more water than a single vial?

Not necessarily, but the combined mass is usually higher, so the same volume gives a higher total concentration. A 10mg blend in 2ml is 5000 mcg/ml combined; whether that is convenient depends on the component figures it produces and whether they fit your barrel.

Are blended vials approved medicines?

No. Neither component is FDA-approved for the uses described online, and neither is a licensed medicine in the UK. This page does arithmetic on figures you enter.

Before you use this

This tool performs arithmetic only. It does not recommend a dose, a frequency, a duration or a supplier. Many peptides discussed online are not approved by the FDA for the uses people describe. Compounded medicines are supplied on prescription and should be prepared exactly as your pharmacy instructs. Talk to a prescriber or pharmacist before preparing or administering anything.