What Is NAD+?

NAD+ stands for nicotinamide adenine dinucleotide, a coenzyme found in every living cell that plays a central role in energy metabolism, DNA repair, and cellular signalling. NAD+ levels naturally decline with age, and this has driven significant interest in longevity and anti-aging clinical contexts.

NAD+ supplementation or therapy typically involves either intravenous infusion of NAD+ directly, or oral supplementation with precursors such as NMN (nicotinamide mononucleotide) or NR (nicotinamide riboside), which the body converts into NAD+. IV NAD+ is the format most commonly offered by longevity clinics due to its more direct route of administration.

Clinical evidence for NAD+ therapy in humans is growing but remains in relatively early stages compared to more established treatments. Animal studies have shown promising results in metabolic and longevity contexts, and some human trials are underway. However, large-scale randomised controlled trials are limited and long-term effects are not yet well characterised.

Longevity clinics offering NAD+ therapy vary widely in how they structure protocols, dosing, and oversight. Some integrate NAD+ into comprehensive longevity programmes with biomarker tracking and physician oversight. Others offer standalone infusion sessions with minimal assessment.

When evaluating a clinic offering NAD+ therapy, ask about the clinician oversight model, what baseline testing is conducted, how the protocol is tailored to individual needs, and what monitoring is included over time.

This page is informational only. Peptide Clinic Finder does not prescribe or sell NAD+ therapy. Use this directory to compare longevity clinic listings and contact providers directly.